long term side effects of semaglutide for weight loss Long-Term Effects: Clinical Evidence – PlexusDx What to Know About Weight

A Phase 2 RCT published in NEJM 2023 reported a mean body weight reduction of approximately 24% at 48 weeks with the 12 mg weekly dose in adults with obesity

New findings from SURPASS-EARLY: A dual GIP/GLP1 receptor agonist compared with intensified conventional care after two years of treatment in early type 2 diabetes

It analysed more than 600,000 veterans with type 2 diabetes and, compared with patients on non-GLP-1 medications, being on GLP-1s was associated with being 14% less likely to develop a substance abuse disorder (SUD)

Men experiencing erectile dysfunction should consult their GP for evidence-based treatments such as PDE5 inhibitors (sildenafil, tadalafil), lifestyle interventions, and specialist referral when needed