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Management Strategies: Ensure proper injection technique (angle, depth, speed) Rotate sites more frequently (different location each day) Allow peptide to reach room temperature before injection Verify needle gauge appropriateness (typically 29-31G) Check for potential sensitivity to bacteriostatic water preservatives Consider switching injection locations (abdomen vs

However, the study design did not allow for the assessment of the effects of semaglutide on bone metabolism, independent of weight loss, as the control group did not experience comparable weight reduction