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Its stable in gastric juice, which degrades most other protein molecules for digestion and absorption, so its commonly used in the treatment of a variety of gastrointestinal illnesses, including ulcers and Crohns disease

The net effect of ERR activation is increased mitochondrial mass and function, enhanced oxidative capacity, greater fatty acid utilization, and improved metabolic flexibility

It also may play a role in tissue damage repair by increasing blood flow to damaged tissues

Given that B12 is prevalent in meat, fish, and dairy products, people who keep a vegan diet often do not have a natural way to get their daily dose of B12